Fw: [情報] Postdoc Associate at WashU Genetics

※ [本文轉錄自 studyabroad 看板 #1VwWLb7c ]

作者: ahot (不做鄉民了) 看板: studyabroad
標題: [情報] Postdoc Associate at WashU Genetics
時間: Tue Dec 29 00:18:42 2020

Position Summary:

The Jin Lab in the Department of Genetics at Washington University School of
Medicine is looking for an energetic and motivated individual to work as a Postdoctoral
Associate within a highly dynamic research team of scientists, computational
biologists, experimentalists, and clinicians.

The Jin Lab works at the intersection of genomics, human genetics,
pediatrics, and neuroscience. We are curious about many things and are
enthusiastic about what we do. We are currently focusing on the formulation,
development, and application of genetic, genomics, and bioinformatics methodsto better analyze and integrate genome and exome sequencing, SNP array,
RNA-sequencing, epigenomic, metabolomics, and proteomics data. Through the
integration of diverse types of transcriptomic and epigenetic functional
annotations, the integrative genomic analysis will provide a better
understanding of the molecular basis of cardiovascular diseases,
neurodevelopmental disorders, and neurodegenerative disorders, with a
specific focus on the interplay between rare protein-coding and
common-noncoding variants. We collaborate with clinicians, multiple genetic
consortia, the Undiagnosed Disease Network, and the Yale Center for MendelianGenomics to assemble thoroughly phenotyped cohorts for gene discovery and setup a robust recruitment platform that includes domestic and international
collaboration and social media. Following integrative genomic analyses, we
use zebrafish to precisely model human mutations. We also collaborate with
experimentalists to design scalable high-throughput assays to model the
effects of disease-associated mutations using a model organism and/or
cell-based experiments to identify genes/pathways that affect disease
susceptibilities.

Dr. Jin’s research experience is available here: https://scjin.github.io/

Information on being a postdoc at Washington University in St. Louis can be
found at postdoc.wustl.edu/prospective-postdocs

Selected publications:

*Co-first authors
a. Jin SC*, J, Homsy J*, Zaidi S*, et al. Contribution of rare inheritedand de novo variants in 2,871 congenital heart disease probands. Nature
Genetics. 2017. PMID: 28991257. (Citations: >270)
b. Jin SC*, Lewis S*, Bakhtiari S*, Zeng X*, et al. Mutations disruptingneuritogenesis genes confer risk for cerebral palsy. Nature Genetics. 2020.
PMID: 32989326.
c. Jin SC*, Dong W*, Kundishora AJ*, Panchagnula S*, Moreno-De-Luca A*, etal. Exome sequencing implicates genetic disruption of prenatal
neuro-gliogenesis in sporadic congenital hydrocephalus. Nature Medicine.
2020. PMID: 33077954.
d. Duran D*, Zeng X*, Jin SC*, Choi J*, et al. Mutation in epigenetic
modifiers and signaling regulators of neurovascular development in Vein of
Galen malformation. Neuron. 2018. PMID: 30578106.

Required Qualifications:

1. The ideal applicant will hold a Ph.D. or MD/Ph.D., have prior research
experience in molecular biology, computational biology, genomics, biomedical
engineering, or related field.

2. We train postdocs with a biology background who would like to develop
bioinformatics skills.

3. We are equally interested in postdocs with a computer science background
who would like to apply these skills to studying human genetics and improvingpersonalized medicine.

4. The candidate will be expected to plan and carry out research tasks
independently and write-up/present findings on a regular basis.

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※ 編輯: ahot (128.252.174.220 美國), 12/29/2020 00:26:44
※ ahot:轉錄至看板 AfterPhD 12/29 00:28※ ahot:轉錄至看板 BioMedInfo 12/29 00:28※ 編輯: ahot (128.252.174.220 美國), 12/29/2020 00:30:53